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Sinclair Method Studies

Published on: 11/06/2025

This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.

Ozempic vs Naltrexone: Understanding the Key Differences for Alcohol Recovery

Ozempic vs Naltrexone: Understanding the Key Differences for Alcohol Recovery

Ozempic vs Naltrexone: Understanding the Key Differences for Alcohol RecoveryBruce Rose
Published on: 16/09/2025

Ozempic and naltrexone are very different medications, each targeting distinct areas of the brain and body. Ozempic is designed to manage type 2 diabetes and promote weight loss by reducing hunger. Naltrexone is specifically designed to reduce cravings and the rewarding effects of alcohol.

The Sinclair Method (TSM)
Could This £3 Pill Be the Answer? What Recent Newspapers Are Saying About Naltrexone and The Sinclair Method

Could This £3 Pill Be the Answer? What Recent Newspapers Are Saying About Naltrexone and The Sinclair Method

Could This £3 Pill Be the Answer? What Recent Newspapers Are Saying About Naltrexone and The Sinclair MethodBruce Rose
Published on: 05/09/2025

Over the past few months, major UK tabloids like The Sun have published several high-profile stories on naltrexone — a £3 tablet nicknamed the "Ozempic for drinkers". It’s been hailed by some as a revolutionary option for those wanting to cut back or quit alcohol.

The Sinclair Method (TSM)
Dr David Sinclair: The Research Legacy Behind The Sinclair Method

Dr David Sinclair: The Research Legacy Behind The Sinclair Method

Dr David Sinclair: The Research Legacy Behind The Sinclair MethodBruce Rose
Published on: 11/06/2025

The Sinclair Method didn’t originate in a corporate lab or a detox facility—it started in a Helsinki research centre. Dr John David Sinclair, a behavioural psychologist from the United States, moved to Finland in the early 1970s after completing his PhD. There, he joined Alko Laboratories, the research arm of Finland’s state alcohol monopoly, which would later become part of the country’s National Public Health Institute.

The Sinclair Method (TSM)
Is Alcohol Dependency Really a Choice? Why So Many Still Struggle?

Is Alcohol Dependency Really a Choice? Why So Many Still Struggle?

Is Alcohol Dependency Really a Choice? Why So Many Still Struggle?Bruce Rose
Published on: 12/05/2025

"Why don’t they just stop?" It’s a familiar question — one that often leads to frustration, judgement, and misunderstanding. For years, alcohol dependency has been viewed through the lens of morality or self-control. But science paints a different picture: alcohol use disorder (AUD) is not a lifestyle choice, but a chronic condition shaped by changes in brain function.

The Sinclair Method (TSM)
Gradual Alcohol Reduction: A Smarter, Science-Backed Way to Take Control

Gradual Alcohol Reduction: A Smarter, Science-Backed Way to Take Control

Published on: 16/04/2025

Let’s face it—quitting alcohol overnight can be intimidating, and for many, it’s simply not sustainable. That’s where gradual alcohol reduction offers a more realistic and compassionate approach. Rather than forcing complete abstinence from the start, this method gives us time to adjust our relationship with alcohol in a way that feels manageable and lasting.

The Sinclair Method (TSM)
Drink Yourself Sober: Exploring The Sinclair Method in the UK and Ireland

Drink Yourself Sober: Exploring The Sinclair Method in the UK and Ireland

Published on: 12/03/2025

The Sinclair Method (TSM) offers a revolutionary way to overcome alcohol dependence. Unlike traditional abstinence-based recovery, TSM allows individuals to continue drinking while taking medication that gradually reduces their desire for alcohol. This process, known as pharmacological extinction, helps individuals regain control over their drinking habits without the pressure of complete sobriety from the start.

The Sinclair Method (TSM)
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