Sinclair Method Studies
This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.
Ozempic vs Naltrexone: Understanding the Key Differences for Alcohol Recovery
Ozempic and naltrexone are very different medications, each targeting distinct areas of the brain and body. Ozempic is designed to manage type 2 diabetes and promote weight loss by reducing hunger. Naltrexone is specifically designed to reduce cravings and the rewarding effects of alcohol.
Could This £3 Pill Be the Answer? What Recent Newspapers Are Saying About Naltrexone and The Sinclair Method
Over the past few months, major UK tabloids like The Sun have published several high-profile stories on naltrexone — a £3 tablet nicknamed the "Ozempic for drinkers". It’s been hailed by some as a revolutionary option for those wanting to cut back or quit alcohol.
Dr David Sinclair: The Research Legacy Behind The Sinclair Method
The Sinclair Method didn’t originate in a corporate lab or a detox facility—it started in a Helsinki research centre. Dr John David Sinclair, a behavioural psychologist from the United States, moved to Finland in the early 1970s after completing his PhD. There, he joined Alko Laboratories, the research arm of Finland’s state alcohol monopoly, which would later become part of the country’s National Public Health Institute.
Is Alcohol Dependency Really a Choice? Why So Many Still Struggle?
"Why don’t they just stop?" It’s a familiar question — one that often leads to frustration, judgement, and misunderstanding. For years, alcohol dependency has been viewed through the lens of morality or self-control. But science paints a different picture: alcohol use disorder (AUD) is not a lifestyle choice, but a chronic condition shaped by changes in brain function.
Gradual Alcohol Reduction: A Smarter, Science-Backed Way to Take Control
Let’s face it—quitting alcohol overnight can be intimidating, and for many, it’s simply not sustainable. That’s where gradual alcohol reduction offers a more realistic and compassionate approach. Rather than forcing complete abstinence from the start, this method gives us time to adjust our relationship with alcohol in a way that feels manageable and lasting.
Drink Yourself Sober: Exploring The Sinclair Method in the UK and Ireland
The Sinclair Method (TSM) offers a revolutionary way to overcome alcohol dependence. Unlike traditional abstinence-based recovery, TSM allows individuals to continue drinking while taking medication that gradually reduces their desire for alcohol. This process, known as pharmacological extinction, helps individuals regain control over their drinking habits without the pressure of complete sobriety from the start.
The Sunday Reset
Every Sunday, we share a 2-minute insight into the logic of the Sinclair Method.
Join thousands of others for our weekly newsletter and change how you see the problem,
because when you change the way you look at things, the things you look at change.
… There’s a reason we’re called Rethink Drink!
